Syphilis Test With Confirmation

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. While it is highly treatable when diagnosed early, untreated syphilis can progress through multiple stages and lead to serious complications affecting the heart, brain, nervous system, and other organs. The ICare Syphilis Test with Confirmation provides accurate screening with automatic confirmatory testing when appropriate, helping ensure reliable results and timely treatment.

Many people with syphilis experience few or no symptoms, particularly during the early stages of infection. Because symptoms can be mild or mistaken for other conditions, laboratory testing is the most dependable way to detect infection.

Whether you've had a potential exposure, are experiencing symptoms, or want routine STI screening, the ICare Syphilis Test with Confirmation provides the answers you need with complete privacy and confidence.

With ICare's concierge mobile laboratory services, confidential STI testing is delivered directly to your home, office, or preferred location.

What Does This Test Measure?

The Syphilis Test with Confirmation uses a two-step testing approach to provide accurate and reliable results.

Initial Syphilis Screening

The first step screens for antibodies produced by your immune system in response to Treponema pallidum infection.

Depending on the laboratory method used, this may involve either:

A treponemal antibody test, which detects antibodies specific to the syphilis bacterium, or
A non-treponemal screening test, such as the Rapid Plasma Reagin (RPR) test, which detects antibodies associated with active infection.
Confirmatory Testing

If the initial screening result is positive or reactive, additional confirmatory testing is automatically performed to verify the result.

Confirmatory testing helps:

Distinguish true infection from false-positive screening results
Improve diagnostic accuracy
Assist your healthcare provider in determining whether infection is current, previous, or requires additional evaluation

Who Should Consider This Test?

The Syphilis Test with Confirmation may be recommended for individuals who:

Have had unprotected sexual contact
Have multiple sexual partners
Have been notified that a sexual partner tested positive for syphilis
Are experiencing symptoms such as:
A painless sore (chancre)
Rash, especially on the palms or soles
Swollen lymph nodes
Fever
Unexplained skin lesions
Are pregnant or planning pregnancy
Have another sexually transmitted infection
Want routine comprehensive STI screening

Because syphilis may not cause noticeable symptoms, testing is recommended based on risk factors as well as symptoms.

Why Is It Important?

Results help your healthcare provider assess your health, support diagnosis, monitor treatment, and guide personalized care.

What's Included

Common Questions